|
KMID : 1195620120050040228
|
|
Clinical and Experimental Otorhinolaryngology
2012 Volume.5 No. 4 p.228 ~ p.233
|
|
|
Nasal and Exhaled Nitric Oxide in Allergic Rhinitis
|
|
Lee Keon-Jung
Cho Seok-Hyun
Lee Seung-Hwan
Tae Kyung
Yoon Ho-Joo
Kim Sang-Heon
Jeong Jin-Hyeok
|
|
|
Abstract
|
|
|
Objectives: The primary aim of this study was to assess whether one can use levels of nasal nitric oxide (nNO) and exhaled nitric oxide (eNO) as a means of evaluation in allergic rhinitis.
Methods: We used a chemiluminescence analyzer to measure nNO and eNO in normal controls (n=34) and allergic rhinitis patients (n=35), and compared these measurements with various parameters of clinical symptoms and laboratory data.
Results: Mean nNO (389±119 ppb) in allergic rhinitis patients was significantly higher than normal controls (276±88 ppb). Without asthma, mean eNO (64.8±55.9 ppb) in allergic rhinitis patients was significantly higher than normal controls (33.0±24.0 ppb). In the persistent allergic rhinitis group, eNO concentration was significantly higher, while nNO concentration was significantly lower than the intermittent group.
Conclusion: We can use nNO and eNO levels for evaluation of allergic rhinitis. However, we should consider the fact that nNO levels can be reduced, when symptoms are severe and long-lasting. Additionally, in allergic rhinitis, eNO can be elevated without asthma.
|
|
|
KEYWORD
|
|
|
Nitirc oxide, Nasal nitric oxide, Exhaled nitric oxide, Allergic rhinitis, Asthma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|